Which knobs fit into which holes in fibrin polymerization?

Pricing/Formula Grids: Which Fit and Which Don't Fit

which city? which right? for which peoples?

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Corneal surgery in keratoconus: which type, which technique, which outcomes?

Keratoconus is a disease characterized by progressive thinning, bulging, and distortion of the cornea. Advanced cases usually present with loss of vision due to high irregular astigmatism. A majority of these cases require surgical intervention. This review provides an update on the current treatment modalities of corneal surgery available for the management of advanced corneal ectasias.

Which Stars Form Black Holes and Neutron Stars?

I describe the current state of our knowledge of the mapping between the initial masses of stars and the compact objects — particularly neutron stars and black holes — that they produce. Most of that knowledge is theoretical in nature, and relies on uncertain assumptions about mass loss through winds, binary mass transfer, and the amount of mass ejected during a supernovae. Observational constr...

Extended knobs-into-holes packing in classical and complex coiled-coil assemblies.

This year marks the 50th anniversary of Crick's seminal paper on the packing of alpha-helices into coiled-coil structures. The central tenet of Crick's work is the interdigitation of side chains, which directs the helix-helix interactions; so called knobs-into-holes packing. Subsequent determinations of coiled-coil-protein sequences and structures confirmed the key features of Crick's model and...